Key Takeaways
GLP-1 prescribing, in five points
  • Read the labeling. Both drugs carry a boxed warning for thyroid C-cell tumors and have defined contraindications.
  • Build the program, not just the prescription: labs, titration, follow-up, consent and documentation.
  • Branded versus compounded is a live question. FDA’s position has changed, so check current guidance.
  • Prescribing authority depends on license. NPs, PAs and physicians prescribe; RNs administer under orders.
  • Training should cover safety and workflow, not only dosing.

What this guide covers

Semaglutide and tirzepatide are prescription medications, and weight-loss programs built on them are one of the most requested services in cash-pay practices. Prescribing them well takes more than a protocol: patient selection, titration, labs, follow-up and a clear position on branded versus compounded product. This guide covers what providers need to know and where training fits.

It is general educational information. It does not replace the product labeling, current FDA guidance or your own clinical judgment.

Patient selection and safety

Branded versus compounded product

Where the medication comes from is now a major decision. FDA’s position on drug shortages and compounding has changed over time, and it determines when compounding semaglutide or tirzepatide is permitted. FDA has also warned about dosing errors and safety concerns with some compounded products. Check FDA’s current guidance and the product sources you use before you build a program around either option. See the FDA page on semaglutide medications.

Whatever you choose, tell patients plainly what they are receiving, keep records of the source, and have your medical director or counsel confirm the arrangement is compliant.

Who can prescribe and who carries out the order

LicenseRole in a GLP-1 program
NPArizona is listed by AANP as a full practice authority state. NPs may evaluate and prescribe within their certification, training and competence.
PAPrescribes within the arrangement set by the Arizona Regulatory Board of Physician Assistants and the practice agreement. Confirm it covers weight-loss prescribing.
MD / DOPrescribes within competence and remains responsible for what they delegate or order.
RNDoes not prescribe. Educates and administers under a prescriber’s order and protocol.

See who can do what in Arizona, by license. If you run a weight-loss program without a prescriber of your own, you need a medical director who actually reviews charts and orders. See weight-loss medical director in Arizona and what a medical director does.

Building the program, not just the prescription

To model the economics with your own numbers, use the ROI calculator. Treat any result as an estimate.

Where training fits

Semaglutide and tirzepatide are covered in our Peptide Therapy Fundamentals course (1.5 days, $3,900, no prior peptide experience required). It includes a module on metabolic and weight-management peptides: the mechanism of semaglutide and tirzepatide, dosing and titration, patient assessment, baseline labs and monitoring, and how they relate to other metabolic peptides. GLP-1 agents are one part of a broader peptide curriculum, not a standalone course.

The Peptides Advanced course ($2,600) builds on it, and the two together are $5,800. Eligibility is MD, DO, NP, PA or RN with an active unrestricted license. See every course on the tuition and comparison page.

Questions to ask any GLP-1 training
  • Does it cover contraindications, titration and what to do about side effects?
  • Does it address labs, follow-up and documentation, not only dosing?
  • Does it take a clear, current position on branded versus compounded product?
  • Does it explain who may prescribe and who may administer in your state?

Sources and verification

Last reviewed: October 28, 2026, by Naomi Fayzulayev, FNP-BC, FNP-C. Verify requirements against the primary sources before relying on them:

Board websites sometimes block automated access, so open them in a normal browser. This guide is general educational information, not legal advice, and does not create a clinician-client or attorney-client relationship. Consult an Arizona healthcare attorney about your situation.

Frequently asked

Related guides
Keep going