- PRP training splits into two lanes: CMA-sanctioned (the only path to legally use the trademarked O-Shot®, P-Shot®, Vampire Facial®, Vampire Facelift®, and Vampire Breastlift® names in marketing) and non-CMA (teaches technique but requires generic language in patient materials). Both are legitimate; they solve different marketing problems.
- Charles Runels' PRP Training Class at prptrainingclass.com is the source — the inventor of every trademarked CMA procedure. Online-first with hands-on options; monthly membership required for trademark license.
- Beso Provider Hub is the AZ-based CMA-sanctioned training center. Naomi is a CMA Certified Trainer (a credential held by a small number of practitioners nationally). Two-day O-Shot + P-Shot combo is $4,800 with live patient injection on both days — the only 2-day live-patient combo format in the CMA network.
- For non-CMA aesthetic PRP: AAFE’s membership track teaches PRP integration into filler work; PracticalCME’s new triple-accredited Regenerative Aesthetics course covers PRP + PDGF + Sculptra + Radiesse. NLI’s Icon Circle bundle includes PRP + PRF certification alongside 8 other injectables.
- For orthopedic/joint PRP (knees, tendons, joints) — that’s a different specialty from aesthetic and sexual wellness PRP, taught by different programs; not covered in this comparison.
- Under Arizona’s regulatory framework, PRP for aesthetics is Level II or III per the 2025 ASBN Advisory Opinion depending on the specific procedure. RNs perform PRP under A.R.S. § 32-1633 delegation; NPs perform independently under § 32-1601 full practice authority. Trademark licensing is a marketing question; scope of practice is a regulatory one — they’re separate.
Who this comparison is for
This is written for the licensed Arizona provider — MD, DO, NP, PA, or RN — choosing where to invest in PRP training. If your interest is aesthetic PRP (Vampire Facial-style facial rejuvenation) or sexual wellness PRP (O-Shot for women, P-Shot for men), this comparison covers your options. If you’re looking for orthopedic PRP training for joint injection, tendon repair, or musculoskeletal applications, the program landscape is different and I’d point you to programs like the American Academy of Orthopedic Medicine (AAOM) or specialty regenerative medicine fellowships instead.
I’m Naomi Fayzulayev, FNP-C. I run Beso Wellness & Beauty in North Phoenix, where I perform O-Shot, P-Shot, and Vampire Facial procedures every week. I’m one of a small number of Cellular Medicine Association Certified Trainers nationally — meaning I’m authorized by Dr. Charles Runels (the inventor of these procedures) to teach other providers the official protocols. I run Beso Provider Hub, one of the CMA-sanctioned training centers I’m about to describe and grade alongside the alternatives. Disclosure upfront: my own program is in the list. I’ll be more honest about its trade-offs than most trainers are about their competitors.
The two lanes of PRP training — and why it matters
PRP training in 2026 splits into two structurally different offerings, and choosing between them is the single most consequential decision you’ll make before enrolling.
Lane 1: CMA-sanctioned training (trademark-licensed)
The Cellular Medicine Association owns federal trademarks on: O-Shot®, Priapus Shot® (P-Shot®), Vampire Facial®, Vampire Facelift®, and Vampire Breastlift®. Only CMA-certified providers with current membership are legally authorized to use these names in advertising, patient materials, provider directory listings, or any consumer-facing communication. Using a trademarked name without an active CMA license is a federal trademark violation.
CMA-sanctioned training includes: standardized protocols developed by Dr. Runels, 1-year CMA membership on completion, trademark license, listing in the official provider directory (OShot.info, PShot.info, Vampire directories), sample consent forms, ongoing monthly webinars with the inventor, and CMA-provided marketing materials. The membership continues at $99–$149/month per procedure to maintain trademark rights beyond year one.
Lane 2: Non-CMA aesthetic PRP training
Non-CMA programs teach PRP technique — centrifuge operation, injection protocols, patient selection, complication management — but do not include trademark licensing. Providers who complete this pathway can still perform PRP procedures legally, but must use generic language in marketing: “PRP facial rejuvenation,” “autologous growth factor treatment,” “PRP for female sexual wellness” instead of the trademarked names. Depending on your market positioning, this may or may not matter.
Non-CMA PRP training is typically bundled inside broader aesthetic or regenerative medicine curricula (AAFE, PracticalCME’s new regenerative aesthetics course, NLI’s Icon Circle bundle) rather than sold as a standalone procedure. Tuition is often lower per procedure than CMA-sanctioned training, but the ongoing monthly membership does not apply.
If your practice will market sexual wellness services (O-Shot for women or P-Shot for men), CMA-sanctioned is the only legitimate pathway because those trademarks are the marketing hook patients search for by name. If your practice will offer PRP facial rejuvenation as one of many aesthetic services and marketing will describe it generically, non-CMA training is more cost-efficient. Some providers do both — CMA-sanctioned for the sexual wellness track, non-CMA integrated for the facial track.
Head-to-head comparison table
Data as of September 2026. Programs listed have Arizona availability (either based in AZ or with hands-on options for AZ providers). Prices are current at publication; verify at the source.
| Program | Lane | Price range | Live patients | Trademark license | AZ availability |
|---|---|---|---|---|---|
| Beso Provider Hub Phoenix (N. Phoenix) |
CMA-sanctioned | $1,900 O-Shot only $1,900 P-Shot only $4,800 2-day combo |
Both days, live patients | Yes — O-Shot®, P-Shot®, Vampire Breastlift®, Vampire Facial-adjacent | Phoenix-based; in-person |
| Charles Runels PRP Training Class Online-first (Fairhope, AL base) |
CMA-sanctioned (source) | Base tuition + $99–$149/mo membership | Online-first; hands-on optional | Yes — every CMA trademark | Remote-friendly; travel for optional hands-on |
| AAFE (American Academy of Facial Esthetics) Scottsdale location |
Non-CMA (integrated) | $3,297+ Silver membership (2 courses) | Live patient | No | Scottsdale-based |
| National Laser Institute Scottsdale HQ campus |
Non-CMA (bundled) | $5,000+ Icon Circle bundle (incl. PRP+PRF) | Yes — paying spa clients | No | Scottsdale-based |
| PracticalCME (Regenerative Aesthetics) Scottsdale (Courtyard Marriott) |
Non-CMA | ~$2,000–$2,500 estimated | 1 patient per attendee | No | Scottsdale-based |
| Empire Medical Training Fly-in national |
Non-CMA (varies by course) | $1,800–$4,000+ course-dependent | Varies | No | Fly-in to select AZ dates |
Program-by-program deep dives
Bias declared again: this is my program. The honest strengths are the CMA Certified Trainer credential (a small number of us nationally — Dr. Runels personally certifies each trainer), the two-day O-Shot + P-Shot combo format with live patient injection on both days, and the fact that we bundle in the Botox add-on protocols (Clitoxin, Bocox, Grotox, Scrotox) and Vampire Breastlift + labia rejuvenation that no other CMA training center bundles together in one immersive. The $700 savings on the combo vs. enrolling in each course separately is real.
Honest weakness: we’re Phoenix-based in-person only. If you can’t travel to Arizona, Dr. Runels’ online-first program at prptrainingclass.com is the better fit for you — you still get the same trademark license and directory listings.
Dr. Charles Runels invented every trademarked CMA procedure and runs the online-first training at prptrainingclass.com. Application-based (24-hour approval), online didactic videos, quiz, physical certificate mailed to your practice, and CMA membership with directory listing on approval. Access to his personal cell phone as a member is a real differentiator. Monthly webinars with the inventor. In-person hands-on training is available separately for providers who want it before treating patients.
Honest weakness: the online-first structure means live patient injection is optional rather than integrated. Providers who prefer to inject live models under direct supervision before treating their own patients will want to add in-person hands-on (from Beso Provider Hub in AZ or an equivalent CMA-sanctioned center elsewhere). The ongoing monthly membership fee also compounds over time — five procedures at $99/mo = $495/mo indefinitely.
AAFE integrates PRP into their broader facial esthetics curriculum. Their Scottsdale location makes them AZ-accessible. ADA CERP and AGD PACE accreditation is uniquely strong for dentists and physicians who need those specific CE hours. Live patient training with structured technique instruction. The membership tier (Silver at $3,297 for two courses) means you can pair PRP with Botox or filler certification for the same membership fee.
Honest weakness: no trademark license means you cannot legally market Vampire Facial® even though the technique you learn is functionally similar. For an aesthetic practice, this may be fine if you position the service as “PRP microneedling” or “PRP facial rejuvenation.” For a sexual wellness practice, this is not the right choice — the O-Shot® and P-Shot® names are the marketing hook and only CMA training gets you the trademark.
NLI’s Icon Inner Circle bundle at $5,000+ includes nine certifications: Botox, dermal fillers, facial balancing, lips, PRP + PRF (Platelet Rich Plasma / Fibrin), Sculptra, PDO threads, microneedling with PRP and salmon, and cosmetic laser. Their Scottsdale HQ campus and paying-patient hands-on rotation is a real differentiator. For a career-changing nurse starting from zero and wanting a broad multi-procedure certification package with brand recognition, this bundle makes sense.
Honest weakness: the PRP portion within the bundle is a chapter in a broader curriculum, not a specialized deep-dive. No CMA trademarks. Cohorts are larger than smaller-group programs. For a provider who already knows they want to be an O-Shot/P-Shot practice specifically, this is not the right fit — you’re paying for eight other certifications you may not need on day one.
PracticalCME’s new triple-accredited Regenerative Aesthetics course covers PRP alongside PDGF, Sculptra, and Radiesse for facial regenerative work. Triple accreditation (ACCME, AANP, ANCC) means the credits count for professional-liability audits and license renewal in a way non-accredited certificates don’t. MD-taught with the small-group format (max 5). Scottsdale-based at the Courtyard Marriott Salt River.
Honest weakness: no CMA trademarks. The PRP portion is one of four regenerative modalities in the course — not a specialized deep-dive. Best fit for providers building a broader regenerative aesthetics practice who want CME hours for their board. For sexual wellness practice, add CMA-sanctioned training separately.
Empire Medical Training is a national brand offering PRP as part of both aesthetic and orthopedic training tracks. National footprint means broad course scheduling flexibility. Their orthopedic-adjacent PRP training is stronger than most aesthetic-only competitors if joint injection is on your service menu.
Honest weakness: Empire flies into Phoenix a limited number of dates per year and their curriculum was not written for the 2025 Arizona State Board of Nursing Advisory Opinion. No CMA trademarks. Live patient depth varies significantly by course — verify at time of enrollment.
Recommendations by situation
If your practice will offer sexual wellness (O-Shot / P-Shot)
CMA-sanctioned training is the only pathway. Between Beso Provider Hub and Dr. Runels’ PRP Training Class, choose based on geography and format preference: Phoenix in-person with live patient depth on both days at Beso; online-first with optional hands-on at Runels. Either gets you the same trademark license and directory listing on completion. Both bundle the required first-year CMA membership.
If your practice will offer aesthetic PRP as one of many services
Non-CMA training is more cost-efficient. PracticalCME’s Regenerative Aesthetics course if you want triple-accredited CME hours. AAFE Silver membership if you’re a dentist or want ADA CERP / AGD PACE credit. NLI Icon Circle bundle if you want the multi-procedure brand-name certification package. All three teach PRP integration technique that you can market generically.
If your practice will offer both sexual wellness and facial aesthetic PRP
The economical path is CMA-sanctioned training (Beso Provider Hub or Runels) for the sexual wellness trademarks, plus a non-CMA aesthetic PRP course pairing it with filler and Sculptra for the facial track. This lets you use the trademarked O-Shot®/P-Shot® names in sexual wellness marketing while generically describing the facial PRP work — and you pay for CMA membership only for the procedures where trademark actually matters to the marketing story.
If you want the deepest orthopedic / joint PRP training
Look outside this comparison. AAOM (American Academy of Orthopedic Medicine), regenerative medicine fellowships, and specialty orthopedic PRP programs are the right fit for musculoskeletal work. The aesthetic and sexual wellness PRP training landscape does not extend meaningfully into joint injection.
What nobody tells you about PRP training
Four things every program (including mine) underdiscloses on the homepage:
1. The centrifuge you buy matters more than the certificate. PRP quality is fundamentally determined by the centrifuge system you use in practice: spin speed, timing, separation technique. Programs teach a specific FDA-cleared system (or class of systems). If you buy a different centrifuge after training, you’ll need to relearn the preparation protocol — the certificate technique is centrifuge-specific. Ask your prospective trainer which system they teach and confirm it matches what you plan to use in your practice.
2. CMA membership is not one-time. The trademarked names come with an ongoing monthly membership requirement to maintain the license. Five different CMA procedures at $99–$149/mo each = $495–$745/mo indefinitely. Budget this into your service line P&L — the training tuition is only the first payment.
3. Under the 2025 ASBN Advisory Opinion, PRP procedures fall under Level II or Level III depending on injection site. Facial injection (Vampire Facial-style) is Level II. Sexual wellness injection is closer to Level III because of the anatomical complexity, though the classification is procedure-specific rather than universally spelled out. All PRP procedures require a written provider order and Good-Faith Exam by a prescriber prior to treatment. Some programs teach exactly this documentation; others leave you to figure it out after graduation. Ask.
4. RN scope for PRP in Arizona is specific. Under A.R.S. § 32-1633, an RN can perform PRP injection under written delegation from a physician, NP, or PA with prescriptive authority — but the delegation must explicitly authorize the anatomical zone. Generic “PRP injection authorized” standing orders will not survive audit review. This applies uniformly across all seven Phoenix-metro cities we discuss in our location pages.
Bottom line
PRP training in Arizona in 2026 is not one market — it’s two markets stacked on top of each other. The CMA-sanctioned market is the only path to trademark-licensed procedure names (O-Shot®, P-Shot®, Vampire Facial®) and matters if your marketing depends on those hooks. The non-CMA market teaches technique cheaper, integrates PRP into broader aesthetic curricula, and matters if your service menu positions PRP generically.
If your practice will meaningfully feature sexual wellness, my honest answer is Beso Provider Hub (in-person AZ) or Charles Runels’ PRP Training Class (online-first). Both are legitimate CMA-sanctioned pathways to the same trademarks. If your practice is aesthetic-only and PRP is one service among many, PracticalCME’s Regenerative Aesthetics course for CME hours, AAFE if you’re a dentist, or NLI Icon Circle if you want the multi-procedure bundle. None of these is universally best. All of them serve a specific type of practice well.
The most important choice isn’t which certificate to earn — it’s which lane matches your practice’s marketing story before you spend a dollar on tuition.
- O-Shot & P-Shot 2-day combo training (Beso Provider Hub) — the flagship CMA-sanctioned combo with live patient injection on both days.
- O-Shot standalone training and P-Shot standalone training — individual CMA-sanctioned procedures.
- PRP training in Arizona — hub page covering Vampire Facelift, Vampire Breastlift, and PRP for hair.
- Medical Director services for Arizona medspas — ongoing MD relationship that pairs with training.
- Best dermal filler training in Arizona — 2026 comparison — companion buyer’s guide for the Level III filler decision.
- Best Botox training in Phoenix — 2026 comparison and State of the Arizona Medspa Industry 2026 Report.